Will cucumbers cross-pollinate with other vine crops?

Question:

Will cucumbers cross-pollinate with other vine crops?

Answer:

Cucumbers will not cross-pollinate with squashes, pumpkins, muskmelons, or watermelons.  Cucumber varieties may cross with one another.  However, the quality of this year’s crop is not affected.  (An exception is the cross-pollination of parthenocarpic cucumber varieties with standard varieties.  Parthenocarpic varieties develop fruit without pollination.  As a result, the non-fertilized fruit do not contain seeds.  Parthenocarpic varieties must be isolated from standard varieties to prevent cross-pollination and seed development.)   

Learn more in this article: Growing Cucumbers in the Home Garden